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<h2>Data Validation through Tissue Analysis</h2>by Stephen Jones 
 
The existing body of literature using Western blot analysis 
has been primarily defined with data from tumor, immortal, and primary cells 
growing in vitro. Collectively, results obtained over decades have been 
integral to the dogma that up- and down-regulation of proteins can be leveraged 
as Biomarkers of normal development, homeostasis, and disease.  However, 
in contrast to tissues which are composed of multiple cell types, cell lines 
growing in culture which theoretically consist of clonal populations. Thus, 
validation or modification of western blot parameters collectively established 
from decades of cell line data in tissue lysates is key for Biomarker 
discovery. 
 
IMGENEX can provide you with normal post mortem, cancerous, diseased, and 
normal adjacent clinical specimens matching your requirements. Custom 
collection protocols are welcomed. Specimens are available as frozen or 
formalin-fixed, paraffin-embedded tissue blocks, and include clinical case and 
detailed pathology reports, as well as final diagnosis and staging.  Learn 
more about this service by visiting our website, or downloading our Tissue 
Procurement literature. 
 
<o:p> </o:p> 
 
Related 
Products 
    *  Tissue Arrays 
    *  Single Tissue Slides 
    *  Tissue & Cell Lysates 
    *  Extraction/ Fractionation Kits 
    *  INSTA-Blot 
Ready2use WB Membranes<o:p /> 
 
 
<h3>About the Author</h3>

IMGENEX India Pvt
Ltd. the only biotech company in Orissa and one of its kinds in <st1:place w:st="on">Eastern India</st1:place>. IMGENEX <st1:country-region w:st="on">India</st1:country-region>
started in Oct as an outsourcing branch of  <a href="http://www.imgenex.com">IMGENEX Corporation</a> , <st1:city w:st="on"><st1:place w:st="on">San Diego</st1:place></st1:city>, USA.Find out
more information about  <a href="http://www.imgenex.com/tissue_array.php">Tissue
Arrays</a>.<o:p />

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