Free Articles at Neutron Marketing Article Publishing and Distribution » Cancer » Data Validation through Tissue Analysis
Previous Article - NF-kB Activation: Elucidating Upstream Events
Next Article - Faces of DARPP-32: Master Signaling Mediator in the Brain?

View PDF | Print View | Html Version
by: Stephen Jones
Total views: 27
Word Count: 200

The existing body of literature using Western blot analysis has been primarily defined with data from tumor, immortal, and primary cells growing in vitro. Collectively, results obtained over decades have been integral to the dogma that up- and down-regulation of proteins can be leveraged as Biomarkers of normal development, homeostasis, and disease.  However, in contrast to tissues which are composed of multiple cell types, cell lines growing in culture which theoretically consist of clonal populations. Thus, validation or modification of western blot parameters collectively established from decades of cell line data in tissue lysates is key for Biomarker discovery.

IMGENEX can provide you with normal post mortem, cancerous, diseased, and normal adjacent clinical specimens matching your requirements. Custom collection protocols are welcomed. Specimens are available as frozen or formalin-fixed, paraffin-embedded tissue blocks, and include clinical case and detailed pathology reports, as well as final diagnosis and staging.  Learn more about this service by visiting our website, or downloading our Tissue Procurement literature.

 

Related Products
    *  Tissue Arrays
    *  Single Tissue Slides
    *  Tissue & Cell Lysates
    *  Extraction/ Fractionation Kits
    *  INSTA-Blot Ready2use WB Membranes

About the Author

IMGENEX India Pvt Ltd. the only biotech company in Orissa and one of its kinds in Eastern India. IMGENEX India started in Oct as an outsourcing branch of  IMGENEX Corporation , San Diego, USA.Find out more information about  Tissue Arrays.

---

Rating: Not yet rated

--Choose-- 0 1 2 3 4 5

No comments posted.

Add Comment

Enter the code shown